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Tadalafil
Clinical data
Pronunciation/ t ə ˈ d æ l ə f ɪ l / tə- DAL -ə-fil
Trade namesCialis, Adcirca
AHFS/Drugs.comMonograph
MedlinePlusa604008
License dataEU  EMA:  by INN
Pregnancy categoryB
Routes of administrationBy mouth (tablets)
ATC codeG04BE08 ( WHO )
Legal status
Legal statusIn general: ℞ (Prescription only)
Pharmacokinetic data
BioavailabilityVaries
Protein binding94%
MetabolismLiver (predominantly CYP3A4)
MetabolitesCatechol metabolite
Elimination half-life17.5 hours
ExcretionFeces (~61%), urine (~36%) [1]

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The maximum dose is 5 mg orally once every 72 hours. Patients should be stable on alpha blocker therapy prior to initiating treatment with this drug.

Tell your doctor if you are breast-feeding. If tadalafil is used as needed, you are not likely to be on a dosing schedule.

This lower selectivity is thought to be the basis for abnormalities related to color vision observed with higher doses or plasma levels. Some data indicate that tadalafil does not potentiate the increase in bleeding time caused by aspirin.

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The safety and efficacy of tadalafil administered concurrently with any other phosphodiesterase inhibitors e. Sanofi-Aventis Pharmaceuticals; Dec. There are no data available for doses higher than 10 mg of tadalafil in patients with hepatic impairment.

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Where we have given you (or where you have chosen) a password which enables you to access certain parts of our site, you are responsible for keeping this password confidential. We strive to provide you with choices regarding the personal information you provide to us. Our Website may contain links or references to other websites outside of our control. The name you see printed on the pill is the active ingredient used there. To a buyer or other successor in the event of a merger, divestiture, restructuring, reorganization, dissolution, or other sale or transfer of some or all of Roman’s assets, whether as a going concern or as part of bankruptcy, liquidation, or similar proceeding, in which personal information held by Roman about our Website users or the App users is among the assets transferred.

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