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|Pronunciation||/ t ə ˈ d æ l ə f ɪ l / tə- DAL -ə-fil|
|Trade names||Cialis, Adcirca|
|License data||EU EMA: by INN|
|Routes of administration||By mouth (tablets)|
|ATC code||G04BE08 ( WHO )|
|Legal status||In general: ℞ (Prescription only)|
|Metabolism||Liver (predominantly CYP3A4)|
|Elimination half-life||17.5 hours|
|Excretion||Feces (~61%), urine (~36%) |
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The maximum dose is 5 mg orally once every 72 hours. Patients should be stable on alpha blocker therapy prior to initiating treatment with this drug.
Tell your doctor if you are breast-feeding. If tadalafil is used as needed, you are not likely to be on a dosing schedule.
This lower selectivity is thought to be the basis for abnormalities related to color vision observed with higher doses or plasma levels. Some data indicate that tadalafil does not potentiate the increase in bleeding time caused by aspirin.
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The safety and efficacy of tadalafil administered concurrently with any other phosphodiesterase inhibitors e. Sanofi-Aventis Pharmaceuticals; Dec. There are no data available for doses higher than 10 mg of tadalafil in patients with hepatic impairment.
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