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|Trade names||Zithromax, Azithrocin, others |
|License data||US FDA: Azithromycin|
|Pregnancy category||AU: B1 US: B (No risk in non-human studies)|
|Routes of administration||By mouth (capsule, tablet or suspension), intravenous, ophthalmic|
|ATC code||J01FA10 ( WHO ) S01AA26 ( WHO )|
|Legal status||US: ℞-only|
|Bioavailability||38% for 250 mg capsules|
|Elimination half-life||11–14 h (single dose) 68 h (multiple dosing)|
|Excretion||Biliary, renal (4.5%)|
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In animal models, this results in high concentrations of azithromycin being delivered to the site of infection. For the treatment of sexually transmitted diseases caused by Chlamydia trachomatis and Haemophilus ducreyi, the dose is 1, mg as a single oral dose.
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Neutropenia was observed in subjects receiving concomitant treatment of azithromycin and rifabutin.
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Azithromycin has been reported to be secreted into human breast milk, but there are no adequate and well-controlled clinical studies in nursing women that have characterized the pharmacokinetics of azithromycin adcirca package insert into human breast milk. The following undesirable effects have been reported in association with DMAC prophylaxis and treatment clinical trials: For the treatment of sexually transmitted diseases caused by Chlamydia trachomatis and Haemophilus ducreyi, the dose is 1, mg as a single oral dose.
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